TH-1 and TH-2 Cytokines in Stable Chronic Alcoholics
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چکیده
منابع مشابه
Pivotal Advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation.
CD14+ peripheral blood monocytes can differentiate into fibroblast-like cells called fibrocytes, which are associated with and are at least partially responsible for wound healing and fibrosis in multiple organ systems. Signals regulating fibrocyte differentiation are poorly understood. In this study, we find that when added to human PBMCs cultured in serum-free medium, the profibrotic cytokine...
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The description of two subtypes of T helper cells based on cytokine profiles by Mosman and Coffman in 1986 was a major step forward in thinking on control of immune responses. Building on previous divisions of responses into predominantly humoral or predominantly cellmediated, they described murine T cells clones that could be divided into either Th-1 producing IFN-y and IL-2 but not IL-4 and I...
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Eumycetoma is a progressive and destructive chronic granulomatous subcutaneous inflammatory disease caused by certain fungi, the most common being Madurella mycetomatis. The host defence mechanisms against fungi usually range from an early non-specific immune response to activation and induction of specific adaptive immune responses by the production of Th-1 and Th-2 cytokines. The aim of this ...
متن کاملبررسی نقش سلو لهای دندریتیک کبد و طحال در القای پاس خهای سلولی 1 TH و 2 TH
Background & Objective: Dendritic cells(DCs) play an important role in directing immune response toward TH1(T-Helper 1) or TH2(T-Helper 2). These cells may induce distinct cytokine patterns in different tissues. So the pattern of cytokine induction by liver and spleen DCs may differ from each other. To investigate the difference between immune responses in the liver(as a non-lymphoid organ ...
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ژورنال
عنوان ژورنال: Alcohol and Alcoholism
سال: 2012
ISSN: 1464-3502,0735-0414
DOI: 10.1093/alcalc/ags041